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v2.1.5153.produswest2
Journal Article
|Research

Integrating hepatitis C treatment into multidrug-resistant TB care

Kirakosyan O, Melikyan N, Falcao J, Khachatryan N, Atshemyan H, Oganezova I, Aznauryan A, Yeghiazaryan L, Sargsyants N, Hayrapetyan A, Balkan S, Hewison CCH, Huerga H
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Abstract
BACKGROUND
Direct-acting antivirals (DAAs) are not widely used for patients with chronic hepatitis C virus (HCV) infection and multidrug- or rifampicin-resistant TB (MDR/RR-TB). We describe the implementation aspects of a new integrated model of care in Armenia and the perceptions of the healthcare staff and patients.

METHODS
We used qualitative methods, including a desktop review and semi-structured individual interviews with healthcare staff and with patients receiving HCV and MDR/RR-TB treatment.

RESULTS
The new integrated model resulted in simplified management of HCV and MDR/RR-TB at public TB facilities. Training on HCV was provided for TB clinic staff. All MDR/RR-TB patients were systematically offered HCV testing and those diagnosed with HCV, offered treatment with DAAs. Treatment monitoring was performed by TB staff in coordination with a hepatologist. The staff interviewed had a positive opinion of the new model. They suggested that additional training should be provided. Most patients were fully satisfied with the care received. Some were concerned about the increased pill burden.

CONCLUSION
Integrating HCV treatment into MDR/ RR-TB care was feasible and appreciated by patients and staff. This new model facilitated HCV diagnosis and treatment among people with MDR/RR-TB. Our results encourage piloting this model in other settings.

Countries

Armenia

Subject Area

antibiotic resistancetuberculosismodels of careantimicrobial resistancehepatitis Chepatitis

Languages

English
DOI
10.5588/pha.22.0002
Published Date
21 Jun 2022
PubMed ID
35734011
Journal
Public Health Action
Volume | Issue | Pages
Volume 12, Issue 2, Pages 96-101
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Integrating hepatitis C treatment into multidrug-resistant TB care | Journal Article / Research | MSF Science Portal