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v2.1.5418.produswest2
Showing 1 - 20 of 422 Items
Showing 1 - 20 of 422 Items
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Journal Article
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Research

The frequency and incidence of QT prolongation with extended use of bedaquiline or delamanid in a large, multi-country multidrug-resistant/rifampicin-resistant tuberculosis cohort

Khan U, Rich M, Franke MF, Lachenal N, Ahmed S,  et al.
2025-08-01 • Clinical Infectious Diseases
2025-08-01 • Clinical Infectious Diseases

BACKGROUND

The 2022 World Health Organization (WHO) guidelines on multidrug-resistant/rifampicin-resistant tubercul...

Journal Article
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Research

Acquisition of Escherichia coli carrying extended-spectrum ß-lactamase and carbapenemase genes by hospitalised children with severe acute malnutrition in Niger

Sands K, Lankapalli AK, Lai G, Hassan B, Portal EA,  et al.
2025-08-01 • Nature Communications
2025-08-01 • Nature Communications

Hospitalisation and routine antibiotic treatment are recommended for&nbs...

Journal Article
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Research

Performance evaluation of the Mini-Lab, an all-in-one clinical bacteriology laboratory adapted to low-resource settings, in a district hospital in Central African Republic: a prospective descriptive study

Langendorf C, Ronat JB, Natale A, Vidal T, Kodo H,  et al.
2025-07-29 • International Journal of Infectious Diseases
2025-07-29 • International Journal of Infectious Diseases

BACKGROUND

Médecins sans Frontières designed an all-in-one microbiology laboratory (the "Mini-Lab") ...

Journal Article
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Review

Optimal dosing and duration of linezolid for the treatment of multidrug-resistant and rifampicin-resistant tuberculosis: An individual patient data meta-analysis

Kwak N, Kim JY, Han A, Berry C, Beumont M,  et al.
2025-07-17 • European Respiratory Journal
2025-07-17 • European Respiratory Journal

BACKGROUND

The optimal dosing strategy of linezolid for treating multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) remains unclear. We condu...

Journal Article
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Research

Bedaquiline, delamanid, linezolid, and clofazimine for rifampicin-resistant and fluoroquinolone-resistant tuberculosis (endTB-Q): an open-label, multicentre, stratified, non-inferiority, randomised, controlled, phase 3 trial

Guglielmetti L, Khan U, Velásquez GE, Gouillou M, Ali MH,  et al.
2025-07-16 • Lancet Respiratory Medicine
2025-07-16 • Lancet Respiratory Medicine
Journal Article
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Review

Clinical best practices for caring for people with expanded resistance to newer TB drugs

Nkomo T, Udwadia Z, Vambe D, van Rie A, Thi S,  et al.
2025-06-13 • IJTLD OPEN
2025-06-13 • IJTLD OPEN

BACKGROUND

Strains of Mycobacterium tuberculosis

Journal Article
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Commentary

Keeping our feet on the ground: the role of innovation in scaling up diagnosis to counter antimicrobial resistance

Alkon A, Cunningham J, Kanapathipillai R, Naim C, Shortall C,  et al.
2025-05-01 • Lancet Microbe
2025-05-01 • Lancet Microbe
Journal Article
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Commentary

Unravelling the linkages between conflict and antimicrobial resistance

Abbara A, Shortall C, Sullivan R, Zwijnenburg W, Moussally K,  et al.
2025-04-12 • NPJ Antimicrobials and Resistance
2025-04-12 • NPJ Antimicrobials and Resistance
Journal Article
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Research

Phenotypic and genotypic resistance to bedaquiline in patients with multi-drug-resistant tuberculosis—experiences from Armenia

Ardizzoni E, Mulders W, De Diego Fuertes M, Hayrapetyan A, Mirzoyan A,  et al.
2025-04-09 • Antimicrobial Agents and Chemotherapy
2025-04-09 • Antimicrobial Agents and Chemotherapy

Risk factors for baseline bedaquiline (BDQ) resistance, amplification during treatment, and correlations with treatment outcomes are not fully understood. This cohort included Armenia...

Journal Article
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Research

Bedaquiline resistance and treatment outcomes among patients with tuberculosis previously exposed to bedaquiline in India: A multicentric retrospective cohort study

Singla R, Khan S, Silsarma A, Chavan V, Mahajan R,  et al.
2025-03-13 • Clinical Infectious Diseases
2025-03-13 • Clinical Infectious Diseases

BACKGROUND

Bedaquiline (BDQ) resistance presents a critical challenge in the fight against tuberculosis (TB), particularly multidrug-resistant (MDR) strains. Th...

Journal Article
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Review

Improving equitable access for effective antibacterial: An ecosystem approach

Cohn J, Balasegaram M, Srinivasan H, Menghaney L, Mpundu M,  et al.
2025-03-01 • Clinical Microbiology and Infection
2025-03-01 • Clinical Microbiology and Infection

BACKGROUND

Antibiotics are indispensable to modern healthcare, yet their equitable access remains a pressing global challenge. Factors contributing to inequitie...

Journal Article
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Research

The effectiveness and safety of bedaquiline, pretomanid, and linezolid (BPaL)-based regimens for rifampicin-resistant tuberculosis in non-trial settings - A prospective cohort study in Belarus and Uzbekistan

Sinha A, Klebe R, Rekart ML, Alvarez JL, Skrahina A,  et al.
2025-02-18 • Clinical Infectious Diseases
2025-02-18 • Clinical Infectious Diseases

BACKGROUND

Only 63% of patients initiating multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) treatment in 2020 were treated successfully. 24-Wee...

Journal Article
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Review

Conflict-associated wounds and burns infected with GLASS pathogens in the Eastern Mediterranean Region: A systematic review

Wild A, Shortall C, Dewachi O, Naim C, Green A,  et al.
2025-02-07 • BMC Infectious Diseases
2025-02-07 • BMC Infectious Diseases

BACKGROUND

While the relationship between conflict-associated injuries and antimicrobial resistance is increasingly being elucidated, data concerning civilian c...

Journal Article
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Letter

Sustained treatment success at 12 months for drug-resistant TB patients on concomitant bedaquiline-delamanid

Chavan V, Silsarma A, Mahajan R, Khan S, Singh P,  et al.
2025-02-01 • IJTLD OPEN
2025-02-01 • IJTLD OPEN
Journal Article
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Research

Oral regimens for rifampin-resistant, fluoroquinolone-susceptible tuberculosis

Guglielmetti L, Khan U, Velásquez GE, Gouillou M, Abubakirov A,  et al.
2025-01-29 • New England Journal of Medicine
2025-01-29 • New England Journal of Medicine

BACKGROUND

For decades, poor treatment options and low-quality evidence plagued care for patients with rifampin-resistant tuberculosis. The advent of new drugs ...

Journal Article
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Review

Antibiotic resistance in the Middle East and Southern Asia: a systematic review and meta-analysis

Mathu R, Diago-Navarro E, Lynch E, Degail MA, Ousley J,  et al.
2024-12-26 • JAC-Antimicrobial Resistance
2024-12-26 • JAC-Antimicrobial Resistance

INTRODUCTION

Despite global surveillance efforts, antibiotic resistance (ABR) is difficult to address in low- and middle-income countries (LMICs). In the absenc...

Conference Material
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Poster

Antibiotic susceptibility patterns of bacterial pathogens isolated from hospitalized patients with advanced HIV disease (AHD) in Bihar, India

Kumar V, Murali S, Goldberg J, Alonso B, Moretó-Planas L,  et al.
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Conference Material
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Poster

Does antibiotic resistance really contribute to mortality among patients with gram-negative blood stream infections: A real world single center study

Bansal N
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Conference Material
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Poster

High-performance antimicrobial surgical supplies for preventing antimicrobial-resistant surgical site infections

Gupta Y, Gupta Y, Ranjan A, Mukhopadhyay S
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024
Conference Material
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Slide Presentation

Antibiotic smart community project

Ali HM
2024-11-08 • MSF Scientific Days Asia 2024
2024-11-08 • MSF Scientific Days Asia 2024