logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5153.produswest2
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5153.produswest2
Showing 1 - 20 of 30 Items
Showing 1 - 20 of 30 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Conference Material
|
Abstract

Measles confirmation and seroprevalence: addressing the challenges of sample collection and laboratory procedures

Langendorf C, Nikolay B
2024-05-23 • Epicentre Scientific Day 2024
2024-05-23 • Epicentre Scientific Day 2024
BACKGROUND
While case confirmation is most of the time not necessary for case management decisions– the measles outbreak response relies on the timely biological confirmation of outb...
Journal Article
|
Review

Impacts of the advancement in artificial intelligence on laboratory medicine in low‐ and middle‐income countries: Challenges and recommendations—A literature review

Oduoye MO, Fatima E, Muzammil MA, Dave T, Irfan H,  et al.
2024-01-04 • Health Science Reports
2024-01-04 • Health Science Reports
BACKGROUND AND AIMS
Artificial intelligence (AI) has emerged as a transformative force in laboratory medicine, promising significant advancements in healthcare delivery. This study e...
Journal Article
|
Review

C-reactive protein and procalcitonin use in adults in low- and middle-income countries: a narrative review

Lamrous A, Repetto EC, Depp T, Jimenez C, Chua AC,  et al.
2023-05-17 • JAC-Antimicrobial Resistance
2023-05-17 • JAC-Antimicrobial Resistance
OBJECTIVES
C-reactive protein (CRP) and procalcitonin (PCT) are widely used biomarkers in high-income countries. However, evidence for their use in low- and middle-income countries (...
Journal Article
|
Research

Ebola Virus Disease in pregnancy: clinical, histopathologic and Immunohistochemical findings

Muehlenbachs A, de la Rosa Vazquez O, Bausch DG, Schafer IJ, Paddock C,  et al.
2016-05-25 • Journal of Infectious Diseases
2016-05-25 • Journal of Infectious Diseases
Here we describe clinicopathologic features of EVD in pregnancy. One woman infected with Sudan virus in Gulu, Uganda in 2000 had a stillbirth and survived, and another woman with Bundibu...
Journal Article
|
Research

Evaluation of the SD Bioline TB Ag MPT64 test for identification of Mycobacterium tuberculosis complex from liquid cultures in southwestern Uganda

Orikiriza P, Nyehangane D, Atwine D, Kisakye JJ, Kassaza K,  et al.
2017-03-31 • East African Medical Journal
2017-03-31 • East African Medical Journal
BACKGROUND
To confirm presence of Mycobacterium tuberculosis complex, some tuberculosis culture laboratories still rely on para-nitrobenzoic acid (PNB), a traditional technique that ...
Journal Article
|
Review

Experience of Médecins Sans Frontières in laboratory medicine in resource-limited settings

Kosack CS
2012-03-16 • Clinical Chemistry and Laboratory Medicine
2012-03-16 • Clinical Chemistry and Laboratory Medicine
In medical humanitarian assistance, the diagnosis of diseases plays a crucial role. Laboratory investigations are one of the main diagnostic tools utilized in Médecins Sans Frontières' (...
Journal Article
|
Review

Clinical bacteriology in low-resource settings: today’s solutions

Ombelet S, Ronat JB, Walsh T, Yansouni CP, Cox J,  et al.
2018-08-01 • Lancet Infectious Diseases
2018-08-01 • Lancet Infectious Diseases
Low-resource settings are disproportionately burdened by infectious diseases and antimicrobial resistance. Good quality clinical bacteriology through a well functioning reference laborat...
Conference Material
|
Video

Integration of an all-in-one bacteriology laboratory (Mini-Lab) in an MSF hospital: evaluation in Carnot, CAR

Langendorf C
2022-06-21 • Epicentre Scientific Day Paris 2022
2022-06-21 • Epicentre Scientific Day Paris 2022
Journal Article
|
Review

AMR in low-resource settings: Médecins Sans Frontières bridges surveillance gaps by developing a turnkey solution, the Mini-Lab

Ronat JB, Natale A, Kesteman T, Andremont A, Elamin W,  et al.
2021-10-01 • Clinical Microbiology and Infection
2021-10-01 • Clinical Microbiology and Infection
BACKGROUND
In low- and middle-income countries (LMICs), data related to antimicrobial resistance (AMR) are often inconsistently collected. Humanitarian, private and non-governmental ...
Conference Material
|
Abstract

Integration of an all-in-one bacteriology laboratory (Mini-Lab) in an MSF hospital: evaluation in Carnot, CAR

Langendorf C
2022-06-01 • Epicentre Scientific Day Paris 2022
2022-06-01 • Epicentre Scientific Day Paris 2022
BACKGROUND
The Mini-Lab is a simplified and modular bacteriology laboratory being developed by MSF to improve access to microbiology diagnostics and antibiotic resistance surveillanc...
Conference Material
|
Video

The antibiotic resistance patterns shown in an acute trauma hospital in Aden, Yemen from 2018 to June 2021

Malaeb R, Nagwan Y
2022-06-21 • Epicentre Scientific Day Paris 2022
2022-06-21 • Epicentre Scientific Day Paris 2022
Journal Article
|
Research

Hidden dangers-prevalence of blood borne pathogens, hepatitis B, C, HIV and syphilis, among blood donors in Sierra Leone in 2016: opportunities for improvement: a retrospective, cross-sectional study

Yambasu EE, Reid AJ, Owiti P, Manzi M, Sia Murray MJ,  et al.
2017-12-31 • Pan African Medical Journal
2017-12-31 • Pan African Medical Journal
INTRODUCTION
Transmissible blood-borne infections are a serious threat to blood transfusion safety in West African countries; and yet blood remains a key therapeutic product in the c...
Journal Article
|
Research

Pharmacokinetics of rifampin and isoniazid in tuberculosis-HIV-coinfected patients receiving nevirapine- or efavirenz-based antiretroviral treatment

Bhatt NB, Barau C, Amin A, Baudin E, Meggi B,  et al.
2014-03-24 • Antimicrobial Agents and Chemotherapy
2014-03-24 • Antimicrobial Agents and Chemotherapy
This is a substudy of the Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Comparison of Nevirapine and Efavirenz for the Treatment of HIV-TB Co-infected Patien...
Journal Article
|
Review

Culture media for clinical bacteriology in low- and middle-income countries: challenges, best practices for preparation and recommendations for improved access

Orekan J, Barbe B, Oeng S, Ronat JB, Letchford J,  et al.
2021-05-18 • Clinical Microbiology and Infection
2021-05-18 • Clinical Microbiology and Infection
BACKGROUND
Culture media are fundamental in clinical microbiology. In laboratories in low- and middle-income countries (LMICs), they are mostly prepared in-house, which is challengin...
Protocol
|
Research Protocol

Considerations in evaluating equipment-free blood culture bottles: A short protocol for use in low-resource settings

Ombelet S, Natale A, Ronat JB, Vandenberg O, Jacobs J,  et al.
2022-04-25 • PLOS One
2022-04-25 • PLOS One
Use of equipment-free, “manual” blood cultures is still widespread in low-resource settings, as requirements for implementation of automated systems are often not met. Quality of manual ...
Journal Article
|
Research

The thin-layer agar method for direct phenotypic detection of multi- and extensively drug-resistant tuberculosis

Ardizzoni E, Mulders W, Kotrikadze T, Goginashvili L, Pangtey H,  et al.
2015-12-02 • International Journal of Tuberculosis and Lung Disease
2015-12-02 • International Journal of Tuberculosis and Lung Disease
BACKGROUND
Molecular techniques rapidly detect resistance to rifampicin (RMP) and isoniazid (INH), but do not eliminate the need for culture-based drug susceptibility testing (DST) a...
Conference Material
|
Abstract

Development of an all-in-one transportable clinical bacteriology laboratory: feedback from testing a mini-lab prototype

Ronat JB, Natale A, Rochard A, Boillot B, Hubert J,  et al.
2019-05-08 • MSF Scientific Days International 2019: Innovation
2019-05-08 • MSF Scientific Days International 2019: Innovation
INTRODUCTION
Within MSF projects, many patients we treat have invasive bacterial infections, often in settings with increasing levels of antimicrobial resistance. However these proje...
Journal Article
|
Research

Biphasic versus monophasic manual blood culture bottles for low-resource settings: an in-vitro study

Ombelet S, Natale A, Ronat JB, Kesteman T, Vandenberg O,  et al.
2021-12-13 • Lancet Microbe
2021-12-13 • Lancet Microbe
BACKGROUND
Manual blood culture bottles (BCBs) are frequently used in low-resource settings. There are few BCB performance evaluations, especially evaluations comparing them with aut...
Journal Article
|
Commentary

The Mini-Lab: accessible clinical bacteriology for low-resource settings

Natale A, Ronat JB, Mazoyer A, Rochard A, Boillot B,  et al.
2020-06-01 • Lancet Microbe
2020-06-01 • Lancet Microbe
Journal Article
|
Review

Best practices of blood cultures in low- and middle-income countries

Ombelet S, Barbe B, Affolabi D, Ronat JB, Lompo P,  et al.
2019-06-18 • Frontiers in Medicine
2019-06-18 • Frontiers in Medicine
Bloodstream infections (BSI) have a substantial impact on morbidity and mortality worldwide. Despite scarcity of data from many low- and middle-income countries (LMICs), there is increas...