logo
Science Portal
Copyright © Médecins Sans Frontières
v2.1.5662.produswest2
About MSF Science Portal
About
Contact Us
Frequently Asked Questions (FAQs)
Privacy Policy
Terms of Use
Copyright © Médecins Sans Frontières
v2.1.5662.produswest2
Showing 1 - 20 of 39 Items
Showing 1 - 20 of 39 Items
Sort By: Relevance
  • Newest to oldest
  • Oldest to newest
  • Relevance
Journal Article
|
Research

Centrifuge-free stool processing methods for Xpert MTB/RIF Ultra tuberculosis diagnosis in children in Uganda and Zambia: an observational, prospective, diagnostic accuracy study

Lounnas M, Masama EN, Beneteau S, Kasakwa K, Kaitano R,  et al.
2025-06-01 • Lancet Microbe
2025-06-01 • Lancet Microbe

BACKGROUND

WHO recommends Xpert MTB/RIF Ultra (Ultra) for stool testing for tuberculosis diagnosis in children. Stool processing requires removal of debris and ...

Journal Article
|
Research

External quality assurance of chest X-ray interpretation to strengthen diagnosis of childhood TB

Melingui B, 
Journal Article
|
Review
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Journal Article
|
Research
Leroy-Terquem E, 
Taguebue J, 
Eap T, 
Borand L, 
et al.
2024-10-01 • IJTLD OPEN
2024-10-01 • IJTLD OPEN

Antimicrobial resistance in Enterobacterales infections among children in sub-Saharan Africa: a systematic review and meta-analysis

Kowalski M, Minka Obama B, Catho G, Dewez JE, Merglen A,  et al.
2024-03-08 • eClinicalMedicine
2024-03-08 • eClinicalMedicine
BACKGROUND
The burden of antimicrobial resistance (AMR) has been estimated to be the highest in sub-Saharan Africa (SSA). The current study estimated the proportion of drug-resistant...

Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial

Marcy O, Wobudeya E, Font H, Vessière A, Chabala C,  et al.
2023-03-01 • Lancet Infectious Diseases
2023-03-01 • Lancet Infectious Diseases
BACKGROUND
Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or ant...

Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis

Hamada Y, Gupta RS, Quartagno M, Izzard A, Acuna-Villaorduna C,  et al.
2023-02-01 • eClinicalMedicine
2023-02-01 • eClinicalMedicine
BACKGROUND
Evidence on the comparative performance of purified protein derivative tuberculin skin tests (TST) and interferon-gamma release assays (IGRA) for predicting incident activ...

African medical educators and anatomy teachers' perceptions and acceptance of the anatomage table as an edTech and innovation: a qualitative study

Owolabi JO, Ojiambo R, Seifu D, Nishimwe A, Masimbi O,  et al.
2022-06-06 • Advances in Medical Education and Practice
2022-06-06 • Advances in Medical Education and Practice
BACKGROUND
This article presents a qualitative study of African anatomists and anatomy teachers on the Anatomage Table-a modern medical education technology and innovation, as an ind...

Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis

Zheng Q, Luquero FJ, Ciglenecki I, Wamala JF, Abubakar A,  et al.
2022-09-01 • International Journal of Infectious Diseases
2022-09-01 • International Journal of Infectious Diseases
BACKGROUND
Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit...

Alternative observational designs to estimate the effectiveness of one dose of oral cholera vaccine in Lusaka, Zambia

Ferreras E, Blake A, Chewe O, Mwaba J, Zulu G,  et al.
2020-03-13 • Epidemiology and Infection
2020-03-13 • Epidemiology and Infection
We conducted a matched case-control (MCC), test-negative case-control (TNCC) and case-cohort study in 2016 in Lusaka, Zambia, following a mass vaccination campaign. Confirmed cholera cas...

Monitoring of antiretroviral therapy and mortality in HIV programmes in Malawi, South Africa and Zambia: mathematical modelling study

Estill J, Egger M, Johnson LF, Gsponer T, Wandeler G,  et al.
2013-02-28 • PLOS One
2013-02-28 • PLOS One
OBJECTIVES
Mortality in patients starting antiretroviral therapy (ART) is higher in Malawi and Zambia than in South Africa. We examined whether different monitoring of ART (viral loa...

Outcomes for efavirenz versus nevirapine-containing regimens for treatment of HIV-1 infection: A systematic review and meta-analysis

Pillay P, Ford NP, Shubber Z, Ferrand RA
2013-07-22 • PLOS One
2013-07-22 • PLOS One
INTRODUCTION
There is conflicting evidence and practice regarding the use of the non-nucleoside reverse transcriptase inhibitors (NNRTI) efavirenz (EFV) and nevirapine (NVP) in first...

Seasonal variations in tuberculosis diagnosis among HIV-positive individuals in Southern Africa: analysis of cohort studies at antiretroviral treatment programmes

Ballif M, Zurcher K, Reid SE, Boulle AM, Fox MP,  et al.
2018-01-11 • BMJ Open
2018-01-11 • BMJ Open
Seasonal variations in tuberculosis diagnoses have been attributed to seasonal climatic changes and indoor crowding during colder winter months. We investigated trends in pulmonary tuber...

Population Differences in Death Rates in HIV-Positive Patients with Tuberculosis

Ciglenecki I, Glynn JR, Mwinga A, Ngwira B, Zumla A,  et al.
2007-10-01 • International Journal of Tuberculosis and Lung Disease
2007-10-01 • International Journal of Tuberculosis and Lung Disease
SETTING: Randomised controlled clinical trial of Mycobacterium vaccae vaccination as an adjunct to anti-tuberculosis treatment in human immunodeficiency virus (HIV) positive patients wit...

Variability of growth in children starting antiretroviral treatment in Southern Africa

Gsponer T, Weigel R, Davies MA, Bolton C, Moultrie H,  et al.
2012-09-17 • Pediatrics
2012-09-17 • Pediatrics
BACKGROUND
Poor growth is an indication for antiretroviral therapy (ART) and a criterion for treatment failure. We examined variability in growth response to ART in 12 programs in Ma...

Implementation research: reactive mass vaccination with single-dose oral cholera vaccine, Zambia

Poncin M, Zulu G, Voûte C, Ferreras E, Muleya CM,  et al.
2017-10-19 • Bulletin of the World Health Organization
2017-10-19 • Bulletin of the World Health Organization
OBJECTIVE
To describe the implementation and feasibility of an innovative mass vaccination strategy - based on single-dose oral cholera vaccine - to curb a cholera epidemic in a larg...

Treatment failure and mortality factors in patients receiving second-line HIV therapy in resource-limited countries

Pujades-Rodríguez M, Balkan S, Arnould L, Brinkhof MW, Calmy A
2010-07-21 • Journal of the American Medical Association (JAMA)
2010-07-21 • Journal of the American Medical Association (JAMA)
CONTEXT
Long-term antiretroviral therapy (ART) use in resource-limited countries leads to increasing numbers of patients with HIV taking second-line therapy. Limited access to furthe...

Evaluation of the SD Bioline cholera rapid diagnostic test during the 2016 cholera outbreak in Lusaka, Zambia

Mwaba J, Ferreras E, Chizema Kawesha E, Mwimbe D, Tafirenyika F,  et al.
2018-05-31 • Tropical Medicine and International Health
2018-05-31 • Tropical Medicine and International Health
OBJECTIVE
To assess the performance of the SD Bioline Cholera Ag O1/O139 rapid diagnostic test (RDT) compared to a reference standard combining culture and PCR for the diagnosis of c...

Simplifying switch to second-line antiretroviral therapy in sub Saharan Africa: predicted effect of using a single viral load to define efavirenz-based first-line failure

Shroufi A, van Cutsem G, Cambiano V, Bansi-Matharu L, Duncan K,  et al.
2019-08-01 • AIDS
2019-08-01 • AIDS
BACKGROUND
Many individuals failing first-line antiretroviral therapy (ART) in sub-Saharan Africa never initiate second-line ART or do so after significant delay. For people on ART w...

Delayed second dose of oral cholera vaccine administered before high-risk period for cholera transmission: Cholera control strategy in Lusaka, 2016

Ferreras E, Matopo B, Chizema Kawesha E, Chewe O, Mzyece H,  et al.
2019-08-30 • PLOS One
2019-08-30 • PLOS One
BACKGROUND:
In April 2016, an emergency vaccination campaign using one dose of Oral Cholera Vaccine (OCV) was organized in response to a cholera outbreak that started in Lusaka in F...

Antiretroviral therapy outcomes in resource-limited settings for HIV-infected children <5 years of age

Sauvageot D, Schaefer MM, Olson D, Pujades-Rodriguez M, O'Brien DP
2010-05-01 • BMC Pediatrics
2010-05-01 • BMC Pediatrics
OBJECTIVE: We describe medium-term outcomes for young children receiving antiretroviral therapy (ART) in resource-limited countries. METHODS: Analyses were conducted on surveillance data...

Correcting mortality for loss to follow-up: a nomogram applied to antiretroviral treatment programmes in sub-Saharan Africa

Egger M, Sidle J, Weigel R, Geng EH, Fox MP,  et al.
2011-01-01 • PLOS Medicine
2011-01-01 • PLOS Medicine
The World Health Organization estimates that in sub-Saharan Africa about 4 million HIV-infected patients had started antiretroviral therapy (ART) by the end of 2008. Loss of patients to ...