Search Results | MSF Science Portal

Journal Article

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Research

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Van Anh DT, et al.

2025-09-01 • Lancet Child and Adolescent Health

BACKGROUND

Prognostic tools for febrile illnesses are urgently required in resource-constrained community contexts. Circulating immune and endothelial activatio...

Journal Article

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Research

Befano B, Kalpathy-Cramer J, Egemen D, Inturrisi F, Jeronimo J, et al.

2025-03-18 • Journal of the National Cancer Institute

The HPV-Automated Visual Evaluation (PAVE) Consortium is validating a cervical screening strategy enabling accurate cervical screening in resource-limited settings. A rapid, low-cost ...

Journal Article

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Research

Chandna A, Koshiaris C, Mahajan R, Ahmad RA, Anh DTV, et al.

2025-02-05 • medRxiv

BACKGROUND

Circulating markers of immune and endothelial activation risk stratify infection syndromes agnostic to disease aetiology. However, their utility in c...

Journal Article

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Research

Cortes-Azuero O, Lefrancq N, Nikolay B, McKee C, Cappelle J, et al.

2024-12-16 • Journal of Infectious Diseases

BACKGROUND

Nipah virus (NiV), a highly lethal virus in humans, circulates in Pteropus bats throughout South and Southeast Asia. Difficulty in obtaining viral genomes from bats m...

Journal Article

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Research

Melingui BF, Basant J, Taguebue Jv, Massom DM, Leroy Terquem E, et al.

2024-11-03 • Journal of Tropical Medicine

OBJECTIVES

Chest x‐ray (CXR) plays an important role in childhood tuberculosis (TB) diagnosis, but access to quality CXR remains a major challenge in resource‐l...

Journal Article

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Research

Melingui B, Leroy-Terquem E, Taguebue J, Eap T, Borand L, et al.

2024-10-01 • IJTLD OPEN

Journal Article

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Research

d’Elbée M, Harker M, Mafirakureva N, Nanfuka M, Nguyet MHTN, et al.

2024-03-21 • eClinicalMedicine

Journal Article

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Research

Wobudeya E, Nanfuka M, Ton Nu Nguyet MH, Taguebue JV, Moh R, et al.

2024-03-21 • ACG Case Reports Journal

BACKGROUND
Childhood tuberculosis (TB) remains underdiagnosed largely because of limited awareness and poor access to all or any of specimen collection, molecular testing, clinical e...

Journal Article

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Research

Melingui BF, Leroy-Terquem E, Palmer M, Taguebue JV, Wachinou AP, et al.

2024-02-01 • IJTLD OPEN

BACKGROUND
Chest X-ray (CXR) interpretation is challenging for the diagnosis of paediatric TB. We assessed the performance of a three half-day CXR training module for healthcare work...

Journal Article

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Research

Pean P, Madec Y, Nerrienet E, Borand L, Laureillard D, et al.

2023-10-13 • Pathogens

IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS compar...

Journal Article

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Research

Joshi B, De Lima YV, Massom DM, Kaing S, Banga MF, et al.

2023-10-11 • PLOS Global Public Health

Decentralizing childhood tuberculosis services, including diagnosis, is now recommended by the WHO and could contribute to increasing tuberculosis detection in high burden countries. How...

Conference Material

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Abstract

Natukunda N

2023-06-08 • Epicentre Scientific Day Paris 2023

BACKGROUND
Childhood tuberculosis is underdiagnosed at low-level healthcare settings because of poor access to specimen collection, rapid molecular testing, clinical evaluation and c...

Conference Material

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Video

Natukunda N

2023-06-08 • Epicentre Scientific Day Paris 2023

Journal Article

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Research

O’Keefe D, Samley K, Bunreth V, Marquardt T, Bobi SE, et al.

2023-04-01 • Bulletin of the World Health Organization

OBJECTIVE
To determine whether a nurse-led model of care for patients with hepatitis C virus (HCV) infections can provide safe and effective diagnosis and treatment in a resource-poo...

Journal Article

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Research

Marcy O, Wobudeya E, Font H, Vessière A, Chabala C, et al.

2023-03-01 • Lancet Infectious Diseases

BACKGROUND
Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or ant...

Journal Article

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Research

Yeung S, Lawford H, Tabernero P, Nguon C, van Wyk A, et al.

2015-06-01 • American Journal of Tropical Medicine and Hygiene

Widespread availability of monotherapies and falsified antimalarials is thought to have contributed to the historical development of multidrug-resistant malaria in Cambodia. This study a...

Journal Article

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Research

Zhang M, O'Keefe D, Iwamoto M, Sann K, Kien A, et al.

2020-05-02 • Journal of Viral Hepatitis

Safe and efficacious pan-genotypic direct-acting antiviral (DAA) regimens, such as sofosbuvir and daclatasvir (SOF+DCV) facilitate simplified models of care for hepatitis C virus (HCV). ...

Journal Article

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Research

Van Damme W, Kheang ST, Janssens B, Kober K

2007-05-01 • Human Resources for Health

BACKGROUND: Funding for scaling-up antiretroviral treatment (ART) in low-income countries has increased substantially, but the lack of human resources for health (HRH) is increasingly be...

Journal Article

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Research

Laureillard D, Marcy O, Madec Y, Chea S, Chan S, et al.

2013-10-23 • AIDS

To analyze cases of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) in the CAMbodian Early versus Late Introduction of Antiretrovirals (CAMELIA)...

Journal Article

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Research

Blanc FX, Sok T, Laureillard D, Borand L, Rekacewicz C, et al.

2011-10-20 • New England Journal of Medicine

Tuberculosis remains an important cause of death among patients infected with the human immunodeficiency virus (HIV). Robust data are lacking with regard to the timing for the initiation...

Science Portal

Risk stratification of childhood infection using host markers of immune and endothelial activation in Asia (Spot Sepsis): a multi-country, prospective, cohort study

Initial evaluation of a new cervical screening strategy combining human papillomavirus genotyping and automated visual evaluation: the Human Papillomavirus–Automated Visual Evaluation Consortium

Risk stratification of childhood infection using host markers of immune and endothelial activation: A multi-country prospective cohort study in Asia (Spot Sepsis)

The genetic diversity of Nipah virus across spatial scales

Implementation of digital chest radiography for childhood tuberculosis diagnosis at district hospital level in six high tuberculosis burden and resources limited countries

External quality assurance of chest X-ray interpretation to strengthen diagnosis of childhood TB

Cost-effectiveness and budget impact of decentralising childhood tuberculosis diagnosis in six high tuberculosis incidence countries: a mathematical modelling study

Effect of decentralising childhood tuberculosis diagnosis to primary health centre versus district hospital levels on disease detection in children from six high tuberculosis incidence countries: an operational research, pre-post intervention study

Evaluation of a short training course of chest X-ray interpretation for the diagnosis of paediatric TB

Natural killer repertoire restoration in TB/HIV co-infected individuals experienced an immune reconstitution syndrome (CAMELIA Trial, ANRS 12153)

Acceptability of decentralizing childhood tuberculosis diagnosis in low-income countries with high tuberculosis incidence: Experiences and perceptions from health care workers in Sub-Saharan Africa and South-East Asia

Impact of decentralisation of childhood TB diagnosis to district hospitals and primary health centers; Example from Uganda

Impact of decentralisation of childhood TB diagnosis to district hospitals and primary health centers; Example from Uganda

Nurse-led initiation of hepatitis C care in rural Cambodia

Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge cluster-randomised trial

Quality of antimalarials at the epicenter of antimalarial drug resistance: results from an overt and mystery client survey in Cambodia

High sustained viral response rate in patients with hepatitis C using generic sofosbuvir and daclatasvir in Phnom Penh, Cambodia

How labour intensive is a doctor-based delivery model for antiretroviral treatment (ART)? Evidence from an observational study in Siem Reap, Cambodia

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome after early initiation of antiretroviral therapy in a randomized clinical trial

Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis