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World Malaria Day 2023 | Collections | MSF Science Portal

World Malaria Day is April 25th. The theme for 2023 is "Zero malaria: invest, innovate, implement" and the importance of reaching marginalized populations with the tools and strategies that are currently available.

This collection highlights research on this theme, especially the latter two "i's": From research on Seasonal Chemoprophylaxis (SMC) and mass drug administration (MDA), to analyzing the reach of gene mutations (HRP2) in new environments, to other interventional research topics, these articles show how innovative approaches can be successfully implemented even in the most challenging settings to fight this global public health threat.

Collection Content

Journal Article
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Commentary

Moving towards malaria elimination with safer treatment for children with G6PD deficiency

Boum Y II, Moukoko CEE, Parikh S
2023-04-01 • Lancet Infectious Diseases
2023-04-01 • Lancet Infectious Diseases
Journal Article
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Research

Effect of large-scale mass drug administration for malaria on mortality and morbidity in Angumu health zone, Ituri, Democratic Republic of Congo

Grout L, Katuala Givo Y, Newport T, Mahamat TA, Gitahi P,  et al.
2023-02-06 • Malaria Journal
2023-02-06 • Malaria Journal
BACKGROUND
Angumu health zone in Ituri, Democratic Republic of Congo, is a highly malaria-endemic area with an overburdened health system and hosting internally displaced persons (ID...
Journal Article
|
Short Report

Plasmodium falciparum pfhrp2 and pfhrp3 Gene Deletions in Malaria-Hyperendemic Region, South Sudan

Molina-de la Fuente I, Benito MJS, Flevaud L, Ousley J, Pasquale HA,  et al.
2023-01-01 • Emerging Infectious Diseases
2023-01-01 • Emerging Infectious Diseases
Pfhrp2 and pfhrp3 gene deletions threaten the use of Plasmodium falciparum malaria rapid diagnostic tests globally. In South Sudan, deletion frequencies were 15.6% for pfhrp2, 20.0% for ...
Journal Article
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Research

Long-lasting insecticidal nets provide protection against malaria for only a single year in Burundi, an African highland setting with marked malaria seasonality

Van Bortel W, Mariën J, Jacobs BKM, Sinzinkayo D, Sinarinzi P,  et al.
2022-12-01 • BMJ Global Health
2022-12-01 • BMJ Global Health
BACKGROUND
Long-lasting insecticidal nets (LLINs) are one of the key interventions in the global fight against malaria. Since 2014, mass distribution campaigns of LLINs aim for unive...
Conference Material
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Video

Implementation quality of seasonal malaria chemoprevention: a qualitative study exploring the perspectives of caregivers and community distributors in Burkina Faso and Chad

Lasmi K
2022-11-29 • MSF Paediatric Days 2022
2022-11-29 • MSF Paediatric Days 2022
Journal Article
|
Research

Evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria and prevalence of pfhrp2/3 deletions in Aweil, South Sudan

Lynch E, Jensen TO, Assao B, Chihana ML, Turuho T,  et al.
2022-09-09 • Malaria Journal
2022-09-09 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are the primary tool for malaria diagnosis in sub-Saharan Africa but the utility of the most commonly used histidine-rich protein ...
Conference Material
|
Video

Mass drug administration as a tool for rapid reduction of malaria morbidity and mortality in emergency settings

Grout L
2022-06-21 • Epicentre Scientific Day Paris 2022
2022-06-21 • Epicentre Scientific Day Paris 2022
Conference Material
|
Video

Understanding and improving case management of severe febrile illness in highly malaria-endemic settings an observational implementation study in the Democratic Republic of the Congo, Nigeria and Uganda

Signorell A
2022-06-07 • MSF Scientific Days International 2022
2022-06-07 • MSF Scientific Days International 2022
Journal Article
|
Research

Prevalence of malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Guindo O, Sayinzoga-Makombe N, Koskalova A,  et al.
2021-10-24 • Malaria Journal
2021-10-24 • Malaria Journal
BACKGROUND
Malaria transmission is highly seasonal in Niger. Despite the introduction of seasonal malaria chemoprevention (SMC) in the Magaria District, malaria incidence remains hig...
Journal Article
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Research

Clinical diagnostic evaluation of HRP2 and pLDH-based rapid diagnostic tests for malaria in an area receiving seasonal malaria chemoprevention in Niger

Coldiron ME, Assao B, Langendorf C, Sayinzoga-Makombe N, Ciglenecki I,  et al.
2019-12-26 • Malaria Journal
2019-12-26 • Malaria Journal
BACKGROUND
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high ...
Journal Article
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Research

Are village health volunteers as good as basic health staffs in providing malaria care? A country wide analysis from Myanmar, 2015

Linn NYY, Kathirvel S, Das M, Thapa B, Rahman MM,  et al.
2018-06-20 • Malaria Journal
2018-06-20 • Malaria Journal
BACKGROUND
Malaria is one of the major public health problems in Myanmar. Village health volunteers (VHV) are the key malaria diagnosis and treatment service provider at community le...
Journal Article
|
Research

Prevalence and diagnostics of congenital malaria in rural Burundi, a cross-sectional study

Stassijns J, van den Boogaard W, Pannus P, Nkunzimana A, Rosanas-Urgell A
2016-08-30 • Malaria Journal
2016-08-30 • Malaria Journal
BACKGROUND
Congenital malaria, defined as the presence of asexual forms of malaria parasites in the peripheral blood during the first 7 days of life, remains a neglected area of rese...
Journal Article
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Research

Global plagues and the Global Fund: Challenges in the fight against HIV, TB and malaria

Ioana Chiotan D, Upshur R, Ford NP
2003-04-01 • BMC International Health and Human Rights
2003-04-01 • BMC International Health and Human Rights
BACKGROUND
Although a grossly disproportionate burden of disease from HIV/AIDS, TB and malaria remains in the Global South, these infectious diseases have finally risen to the top of...

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Advancing Research to Improve NTD Treatments in Children by S...

Dr. Saschveen Singh is a tropical infectious disease advisor for MSF. Read more of MSF's recent work on neglected tropical diseases in pediatric populations, and of Dr. Singh's work at MSF.

New tools and approaches to drug-resistant TB
New tools and approaches to drug-resistant TB
The World Health Organization estimates that 410,000 people developed a drug-resistant tuberculosis infection (DR-TB) in 2022, only 40% of whom were diagnosed and started on treatment—and only 63% then cured. Given all these points of failure, innovation in preventing, diagnosing and treating DR-TB cannot come fast enough. To mark World TB Day (24 March 2024) the content collection linked below highlights recent work by MSF and collaborators to help change this grim picture. The TB-PRACTECAL and endTB studies delivered robust evidence for shorter, safer, more effective drug regimens that are already saving lives worldwide. Other studies explore new approaches to preventive treatment and simpler, quicker, accurate detection of TB and drug resistance—especially among difficult-to-diagnose populations such as children and people living with HIV. But to impact DR-TB globally these innovations must become widely accessible. This requires changes on many fronts, as described in an accompanying Collection (Expanding Access to Lifesaving New TB Tools).
World Hepatitis Day 2024
World Hepatitis Day 2024

Viral hepatitis is a significant cause of disease and death globally. Yet powerful new medical tools to combat hepatitis C and E still reach only a tiny fraction of people who desperately need them, especially in low-resource and emergency settings.


To mark World Hepatitis Day (July 28th) we highlight recent MSF research on making these breakthrough products more widely accessible and simpler to use.


For hepatitis C, where groundbreaking antiviral drugs can cure nearly all patients, MSF is developing comprehensive, community-based models of care that offer rapid screening, diagnosis, and treatment under one roof. In some settings programs focus on the specific needs of highly vulnerable populations, such as people living in remote areas, forcibly displaced refugees, or those co-infected with HIV or TB or who inject drugs.


Turning to prevention, MSF is exploring ways to use the Hepatitis E vaccine more effectively in areas where poor sanitation and water quality regularly lead to outbreaks. Studies in a South Sudanese camp for internally displaced people are strengthening evidence for the vaccine’s feasibility, efficacy, safety and community acceptance, especially for pregnant women and their fetuses. Another report analyzes strategies for overcoming barriers to widespread vaccine adoption.

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World Malaria Day 2023

World Malaria Day 2023